tamiflu ® دراسة تغيرات بروتيوم الكبد تحت تأثير

Abstract

The fear of the community concerning the extent of the vaccine tamiflu (R), that poisoning and causes damages leds us to undertake this research to study the influence of Brocnat tamiflu (R) on the proteine of the white Rat liver (Rat wister) changes. The study includes two parts; the theorical part and the practical one. The theorical part concerns the toxicity study and gives an overview of the viruses and about their anticorps which contain tamiflu. The morphological and anatomical surveys were realized on the rat liver. Determination of some specific functions especially those used for the conversion of the toxicity and some diseases which affect it like cancer was also studied. Regarding to the practical part, doses of tamiflu ®. were identified and the proteins were separated from the reference and treated rate liver using the electrophoreses technics gel with polyacrylamide and SDS solutions. The results obtained in the present study showed clear changes in the production of the total proteins in the treated rat liver. In the fact, the finding point out that the tamiflu has effect on the liver cells gene expression.